Business Licenses are issued for businesses in Unincorporated San Mateo County Only. All Applications for Business Licenses are reviewed and approved by the Office of Planning and Building. There is a $50.00 NON-REFUNDABLE fee for Business License Applications. To ensure a Business License is required prior to purchasing an application, you may contact the Office of Planning and Building at 650-363-4161 or contact the Tax Collector’s Office at 866-220-0308.